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Early progression of chronic histologic lesions in kidney transplant biopsies is not associated with HLA histocompatibility
Background
Early progression of chronic histologic lesions in kidney allografts represents the main finding in graft attrition. The …
Rhea Jabbour, Andreas Heinzel, Roman Reindl-Schwaighofer, Mariella Gloria Gregorich, Heinz Regele, Nicolas Kozakowski, Johannes Kläger, Gottfried Fischer, Alexander Kainz, Jan U Becker, Chris Wiebe, Rainer Oberbauer
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Flexible parametrization of graph-theoretical features from individual-specific networks for prediction
Statistical techniques are needed to analyze data structures with complex dependencies such that clinically useful information can be …
Mariella Gloria Gregorich, Sean L. Simpson, Georg Heinze
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Prediction modelling with many correlated and zero-inflated predictors: assessing a nonnegative garrote approach
Building prediction models from mass-spectrometry data is challenging due to the abundance of correlated features with varying degrees …
Mariella Gloria Gregorich, Michael Kammer, Harald Mischak, Georg Heinze
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Development and validation of a prediction model for future estimated glomerular filtration rate in people with type 2 diabetes and chronic kidney disease
Importance Type 2 diabetes increases the risk of progressive diabetic kidney disease, but reliable prediction tools that can be used …
Mariella Gloria Gregorich, Michael Kammer, Andreas Heinzel, Carsten Böger, Kai-Uwe Eckardt, Hiddo Lambers Heerspink, Bettina Jung, Gert Mayer, Heike Meiselbach, Matthias Schmid, Ulla T Schultheiss, Georg Heinze, Rainer Oberbauer, BEAt-DKD Consortium
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Different roles of protein biomarkers predicting eGFR trajectories in people with chronic kidney disease and diabetes mellitus: a nationwide retrospective cohort study
Background
Chronic kidney disease (CKD) is a common comorbidity in people with diabetes mellitus, and a key risk factor for further …
Michael Kammer, Andreas Heinzel, Karin Hu, Heike Meiselbach, Mariella Gloria Gregorich, Martin Busch, Kevin L Duffin, Maria F Gomez, Kai-Uwe Eckardt, Rainer Oberbauer, BEAt-DKD Consortium
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Individual-specific networks for prediction modelling – A scoping review of methods
Background: Recent advances in biotechnology enable the acquisition of high-dimensional data on individuals, posing challenges for …
Mariella Gloria Gregorich, Federico Melograna, Martina Sunqvist, Stefan Michiels, Kristel Van Steen, Georg Heinze
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Effects of reduced-dose anti-human T-lymphocyte globulin on overall and donor-specific T-cell repertoire reconstitution in sensitized kidney transplant recipients
Background: Pre-sensitized kidney transplant recipients have a higher risk for rejection following kidney transplantation and therefore …
Constantin Aschauer, Kira Jelencsics, Karin Hu, Mariella Gloria Gregorich, Roman Reindl-Schwaighofer, Sabine Wenda, Thomas Wekerle, Andreas Heinzel, Rainer Oberbauer
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Prospective tracking of donor-reactive T-cell clones in the circulation and rejecting human kidney allografts
Background: Antigen recognition of allo-peptides and HLA molecules leads to the activation of donor-reactive T-cells following …
Constantin Aschauer, Kira Jelencsics, Karin Hu, Andreas Heinzel, Mariella Gloria Gregorich, Julia Vetter, Susanne Schaller, Stephan M Winkler, Johannes Weinberger, Lisabeth Pimenov, Guido a Gualdoni, Michael Eder, Alexander Kainz, Anna Regina Troescher, Heinz Regele, Roman Reindl-Schwaighofer, Thomas Wekerle, Johannes Bernhard Huppa, Megan Sykes, Rainer Oberbauer
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